Bine Bryndorf was born in Elsinore (Helsingør) and took her first organ lessons with Kristian Olesen and Bo Grønbech. In 1987-1991 she studied organ with Michael Radulescu and harpsichord with Gordon Murray at the Hochschule für Musik in Vienna. Later came studies with William Porter in Boston and Daniel Roth in Paris. After taking her diploma in sacred music, organ, and harpsichord, Bine Bryndorf was an assistant to Michael Radulescu in Vienna. In 1994 she was appointed as an associate professor at the Royal Danish Academy of Music in Copenhagen, and in January 2001 she was appointed a professor at the same institution. Since 1996 she has also been the organist at Vartov Church, Copenhagen.
Bine Bryndorf has won prizes in organ competitions in Innsbruck, Bruges, and Odense and in chamber music competitions in Melk and Copenhagen (P2 Music, DR). In 1999-2000 she was The Danish Radio's first Artist in Residence. Bine has a wide-ranging career as a soloist and chamber musician, teaches master classes in Europe and the USA and is a jury member in organ competitions.
At present Bine Bryndorf is recording Buxtehude's complete organ music for Buxtehude in a series of 6 CDs.